A study of 1,552 volunteers revealed a low social status can accelerate the ageing process by about seven years. The UK/US team analysed key pieces of DNA called telomeres which are thought to correlate to biological age. The scientists, writing in the journal Aging Cell, believe the stress associated with belonging to a lower social class may be to blame.

Socio-economic status has been shown to have a major impact on health, and there is evidence that a lower status is associated with increased risks of some diseases, infant mortality and life-span. But this research reveals how it may also influence the ageing process itself.

Scientists compared the social class of the volunteers with the average length of their telomeres. Telomeres are repeat sequences of DNA that sit on the ends of chromosomes, protecting them from damage. As people age, their telomeres become shorter and shorter, leaving cells more susceptible to damage and death - the causes of ageing and disease. Because of this, telomere length is used by some scientists as an indicator of biological ageing.

Previous research by the same group found diminished telomere length was linked to smoking and obesity, so they adjusted the data from the female volunteers to take into account factors such as chronological age, body mass index, smoking and exercise. Once they had done so, they discovered that the volunteers' telomere length corresponded to their social class. At the womens' average age of 46, they found the difference between the telomere length of those classified as manual workers - correlating to women in the three lowest social groupings, and non-manual workers - the women in the highest three classes, was equivalent to seven biological years.

To check that this was not caused by genetic factors, the researchers looked at 17 pairs of identical female twins, who had begun life in the same socio-economic class but were currently in different social groups. They found on average, the telomeres of the twin in the higher social class were significantly longer than those in the lower social group - the difference equated to about nine biological years.

Professor Tim Spector, lead researcher on the study and director of the Twin Research Unit, St Thomas' Hospital, London, said: "Not only does social class effect health and age-related disease, but seems to have an impact on the ageing process itself".

Source: BBC